Adult & adolescent ≥16 yr OA 30 mg once daily. May be increased to 60 mg once daily in patients w/ insufficient relief from symptoms.
RA 60 mg once daily. May be increased to 90 mg once daily in patients w/ insufficient relief from symptoms. Once patient is clinically stabilized, down-titration to 60 mg once daily may be appropriate.
Ankylosing spondylitis 60 mg once daily. May be increased to 90 mg once daily in patients w/ insufficient relief from symptoms. Once patient is clinically stabilized, down-titration to 60 mg once daily may be appropriate.
Acute pain conditions Should only be used for acute symptomatic period.
Acute gouty arthritis 120 mg once daily.
Post-op dental surgery pain 90 mg once daily for a max of 3 days.
Mild hepatic dysfunction (Child-Pugh score 5-6) Max: 60 mg once daily.
Moderate hepatic dysfunction (Child-Pugh score 7-9) Max: 30 mg once daily.
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